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Chemical structure of EGFR-IN-89

GC75597

EGFR-IN-89

Also known as N-[2-[[2-[4-(4-ethylpiperazin-1-yl)-3-fluoroanilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]phenyl]-N-methylmethanesulfonamide

EGFR-IN-89 (compound 13k) is a potent, fourth-generation EGFR mutation inhibitor with an IC50 of 10·1 nM against Del19/T790M/C797S mutations

ChemicalCAS2413029-40-8MW538.64FormulaC26H31FN8O2S
CAS number
2413029-40-8
Molecular weight
538.64
Formula
C26H31FN8O2S
Solubility
DMSO： 100 mg/mL (185·65 mM; ultrasonic and warming and heat to 60°C)
InChIKey
IGBZJJZEZHTAIC-UHFFFAOYSA-N
Catalogue number
GC75597
Brand
GLPBIO
Computed properties PubChem CID 150542094 · XLogP 4 · TPSA 118 Ų · H-bond donors 3
XLogP
4
TPSA
118 Ų
H-bond donors
3
H-bond acceptors
10
Rotatable bonds
8
Heavy atoms
38

SMILES CCN1CCN(CC1)C2=C(C=C(C=C2)NC3=NC4=C(C=CN4)C(=N3)NC5=CC=CC=C5N(C)S(=O)(=O)C)F

Computed descriptors from PubChem (CID 150542094), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.