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Chemical structure of EGFR-IN-8

GC39568

EGFR-IN-8

Also known as N-[3-chloro-4-[5-[3-[[4-(cyclopropanecarbonylamino)-3-(trifluoromethyl)phenyl]carbamoylamino]phenyl]-1,2,4-oxadiazol-3-yl]phenyl]pyridine-3-carboxamide

EGFR-IN-8 is a dual EGFR and c-Met inhibitor, compound 48· EGFR-IN-8 can be a promising candidate for further development to target EGFR TKI-resistant NSCLC

ChemicalCAS2407957-87-1MW662.02FormulaC32H23ClF3N7O4
CAS number
2407957-87-1
Molecular weight
662.02
Formula
C32H23ClF3N7O4
Solubility
DMSO： 8·33 mg/mL (12·58 mM)
InChIKey
IIUNSVLRVWGJRM-UHFFFAOYSA-N
Catalogue number
GC39568
Brand
GLPBIO
Computed properties PubChem CID 139035057 · XLogP 4.9 · TPSA 151 Ų · H-bond donors 4
XLogP
4.9
TPSA
151 Ų
H-bond donors
4
H-bond acceptors
10
Rotatable bonds
8
Heavy atoms
47

SMILES C1CC1C(=O)NC2=C(C=C(C=C2)NC(=O)NC3=CC=CC(=C3)C4=NC(=NO4)C5=C(C=C(C=C5)NC(=O)C6=CN=CC=C6)Cl)C(F)(F)F

Computed descriptors from PubChem (CID 139035057), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.