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Chemical structure of EGFR-IN-9

GC65974

EGFR-IN-9

Also known as N-[3-[4-[[(1S)-2-hydroxy-1-phenylethyl]amino]-6-phenylfuro[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

EGFR-IN-9 (Compound 8) is a potent EGFR kinase inhibitor with IC50s of 7 nM, 28 nM for the wild type EGFR kinase and double mutant EGFR kinase (L858R/T790M)· EGFR-IN-9 has antitumor activity

ChemicalCAS1226549-39-8MW476.53FormulaC29H24N4O3
CAS number
1226549-39-8
Molecular weight
476.53
Formula
C29H24N4O3
Solubility
DMSO ： 100 mg/mL (209·85 mM; Need ultrasonic)
InChIKey
GFTOODFOXIDLNF-HSZRJFAPSA-N
Catalogue number
GC65974
Brand
GLPBIO
Computed properties PubChem CID 46212970 · XLogP 5.2 · TPSA 100 Ų · H-bond donors 3
XLogP
5.2
TPSA
100 Ų
H-bond donors
3
H-bond acceptors
6
Rotatable bonds
8
Heavy atoms
36

SMILES C=CC(=O)NC1=CC=CC(=C1)C2=C(OC3=NC=NC(=C23)N[C@H](CO)C4=CC=CC=C4)C5=CC=CC=C5

Computed descriptors from PubChem (CID 46212970), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.