GC73753
EGFR/AURKB-IN-1
Also known as 6-(2-methylpyrazol-3-yl)-N-(4-phenylmethoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
EGFR/AURKB-IN-1 (compound 7) is a dual-targeted EGFR/AURKB inhibitor, and inhibits the phpsphorylations of L858R EGFR and AURKB with IC50s of 0·07 and 1·1, respectively
ChemicalCAS3008543-34-5MW396.44FormulaC23H20N6O
- CAS number
- 3008543-34-5
- Molecular weight
- 396.44
- Formula
- C23H20N6O
- Solubility
- DMSO ： 100 mg/mL (252·24 mM; Need ultrasonic)
- InChIKey
- XIVMLVCBASNGOD-UHFFFAOYSA-N
- Catalogue number
- GC73753
- Brand
- GLPBIO
Computed properties PubChem CID 170385357 · XLogP 4 · TPSA 80.7 Ų · H-bond donors 2
- XLogP
- 4
- TPSA
- 80.7 Ų
- H-bond donors
- 2
- H-bond acceptors
- 5
- Rotatable bonds
- 6
- Heavy atoms
- 30
SMILES CN1C(=CC=N1)C2=CC3=C(N2)N=CN=C3NC4=CC=C(C=C4)OCC5=CC=CC=C5
Computed descriptors from PubChem (CID 170385357), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il