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Chemical structure of JH-XII-03-02

GC73550

JH-XII-03-02

Also known as 2-(2,6-dioxopiperidin-3-yl)-4-[2-[2-[2-[2-[3-[4-[6-[5-(1-methylcyclopropyl)oxy-1H-indazol-3-yl]pyrimidin-4-yl]piperazin-1-yl]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethylamino]isoindole-1,3-dione

JH-XII-03-02 is a potent and selective LRRK2 PROTAC degrader

ChemicalCAS2415900-86-4MW853.92FormulaC43H51N9O10
CAS number
2415900-86-4
Molecular weight
853.92
Formula
C43H51N9O10
Solubility
DMSO ： 100 mg/mL (117·11 mM; Need ultrasonic)
InChIKey
XYGRYBJBOSXMHE-UHFFFAOYSA-N
Catalogue number
GC73550
Brand
GLPBIO
Computed properties PubChem CID 146552766 · XLogP 1.7 · TPSA 220 Ų · H-bond donors 3
XLogP
1.7
TPSA
220 Ų
H-bond donors
3
H-bond acceptors
15
Rotatable bonds
21
Heavy atoms
62

SMILES CC1(CC1)OC2=CC3=C(C=C2)NN=C3C4=CC(=NC=N4)N5CCN(CC5)C(=O)CCOCCOCCOCCOCCNC6=CC=CC7=C6C(=O)N(C7=O)C8CCC(=O)NC8=O

Computed descriptors from PubChem (CID 146552766), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.