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Chemical structure of JH-LPH-28

GC69313

JH-LPH-28

Also known as 1-[5-[4-[3-fluoro-5-(trifluoromethyl)phenyl]piperazin-1-yl]sulfonyl-2,3-dihydroindol-1-yl]ethanone

JH-LPH-28 is a sulfonamide derivative and an effective inhibitor of UDP-2,3-diacylglucosamine hydrolysis enzyme LpxH· It has excellent antibiotic activity with a MIC value of 0·83 μg/mL

ChemicalCAS2414592-36-0MW471.47FormulaC21H21F4N3O3S
CAS number
2414592-36-0
Molecular weight
471.47
Formula
C21H21F4N3O3S
Solubility
DMSO ： 12·5 mg/mL (26·51 mM; ultrasonic and warming and heat to 60°C)
InChIKey
NYMCJUUEVIRRQM-UHFFFAOYSA-N
Catalogue number
GC69313
Brand
GLPBIO
Computed properties PubChem CID 146014474 · XLogP 3 · TPSA 69.3 Ų · H-bond donors 0
XLogP
3
TPSA
69.3 Ų
H-bond donors
0
H-bond acceptors
9
Rotatable bonds
3
Heavy atoms
32

SMILES CC(=O)N1CCC2=C1C=CC(=C2)S(=O)(=O)N3CCN(CC3)C4=CC(=CC(=C4)C(F)(F)F)F

Computed descriptors from PubChem (CID 146014474), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.