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Chemical structure of JH-LPH-33

GC69314

JH-LPH-33

Also known as 1-[5-[4-[3-chloro-5-(trifluoromethyl)phenyl]piperazin-1-yl]sulfonyl-2,3-dihydroindol-1-yl]ethanone

JH-LPH-33 is a sulfonamide derivative and an effective inhibitor of UDP-2,3-diacylglucosamine hydrolysis enzyme LpxH· It has excellent antibiotic activity with a MIC value of 0·66 μg/mL

ChemicalCAS2414590-04-6MW487.92FormulaC21H21ClF3N3O3S
CAS number
2414590-04-6
Molecular weight
487.92
Formula
C21H21ClF3N3O3S
Solubility
DMSO ： 2 mg/mL (4·10 mM; ultrasonic and warming and heat to 60°C)
InChIKey
PDEIRNVIXFZSSJ-UHFFFAOYSA-N
Catalogue number
GC69314
Brand
GLPBIO
Computed properties PubChem CID 145946109 · XLogP 3.6 · TPSA 69.3 Ų · H-bond donors 0
XLogP
3.6
TPSA
69.3 Ų
H-bond donors
0
H-bond acceptors
8
Rotatable bonds
3
Heavy atoms
32

SMILES CC(=O)N1CCC2=C1C=CC(=C2)S(=O)(=O)N3CCN(CC3)C4=CC(=CC(=C4)C(F)(F)F)Cl

Computed descriptors from PubChem (CID 145946109), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.