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Chemical structure of JHU-083

GC36368

JHU-083

Also known as ethyl (2S)-2-[[(2S)-2-amino-4-methylpentanoyl]amino]-6-diazo-5-oxohexanoate

JHU-083, a prodrug of 6-diazo-5-oxo-L-norleucine is an orally active and selective glutaminase antagonist

ChemicalCAS1998725-11-3MW312.36FormulaC14H24N4O4
CAS number
1998725-11-3
Molecular weight
312.36
Formula
C14H24N4O4
Solubility
DMSO： 100 mg/mL (320·14 mM)
InChIKey
YZRCHOFKIPHQBW-RYUDHWBXSA-N
Catalogue number
GC36368
Brand
GLPBIO
Computed properties PubChem CID 137283416 · XLogP 0.7 · TPSA 100 Ų · H-bond donors 2
XLogP
0.7
TPSA
100 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
11
Heavy atoms
22

SMILES CCOC(=O)[C@H](CCC(=O)C=[N+]=[N-])NC(=O)[C@H](CC(C)C)N

Computed descriptors from PubChem (CID 137283416), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.