
GC39385
GLPG1205
Also known as 9-(2-cyclopropylethynyl)-2-[[(2S)-1,4-dioxan-2-yl]methoxy]-6,7-dihydropyrimido[6,1-a]isoquinolin-4-one
GLPG1205 is potent, selective and orally active GPR84 (a G-protein-coupled receptor) antagonist with a favorable PK/PD profile
ChemicalCAS1445847-37-9MW378.42FormulaC22H22N2O4
- CAS number
- 1445847-37-9
- Molecular weight
- 378.42
- Formula
- C22H22N2O4
- Solubility
- DMSO: 250 mg/mL (660·64 mM)
- InChIKey
- IRBAWVGZNJIROV-SFHVURJKSA-N
- Catalogue number
- GC39385
- Brand
- GLPBIO
Computed properties PubChem CID 71616860 · XLogP 2.4 · TPSA 60.4 Ų · H-bond donors 0
- XLogP
- 2.4
- TPSA
- 60.4 Ų
- H-bond donors
- 0
- H-bond acceptors
- 4
- Rotatable bonds
- 4
- Heavy atoms
- 28
SMILES C1CC1C#CC2=CC3=C(C=C2)C4=CC(=NC(=O)N4CC3)OC[C@@H]5COCCO5
Computed descriptors from PubChem (CID 71616860), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il