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Chemical structure of GLPG1205

GC39385

GLPG1205

Also known as 9-(2-cyclopropylethynyl)-2-[[(2S)-1,4-dioxan-2-yl]methoxy]-6,7-dihydropyrimido[6,1-a]isoquinolin-4-one

GLPG1205 is potent, selective and orally active GPR84 (a G-protein-coupled receptor) antagonist with a favorable PK/PD profile

ChemicalCAS1445847-37-9MW378.42FormulaC22H22N2O4
CAS number
1445847-37-9
Molecular weight
378.42
Formula
C22H22N2O4
Solubility
DMSO: 250 mg/mL (660·64 mM)
InChIKey
IRBAWVGZNJIROV-SFHVURJKSA-N
Catalogue number
GC39385
Brand
GLPBIO
Computed properties PubChem CID 71616860 · XLogP 2.4 · TPSA 60.4 Ų · H-bond donors 0
XLogP
2.4
TPSA
60.4 Ų
H-bond donors
0
H-bond acceptors
4
Rotatable bonds
4
Heavy atoms
28

SMILES C1CC1C#CC2=CC3=C(C=C2)C4=CC(=NC(=O)N4CC3)OC[C@@H]5COCCO5

Computed descriptors from PubChem (CID 71616860), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.