Loading...
Chemical structure of GLPG1837

GC19169

GLPG1837

Also known as N-(3-carbamoyl-5,5,7,7-tetramethyl-4H-thieno[2,3-c]pyran-2-yl)-1H-pyrazole-5-carboxamide

GLPG1837 is a potent and reversible CFTR potentiator, with EC50s of 3 nM and 339 nM for F508del and G551D CFTR, respectively

ChemicalCAS1654725-02-6MW348.42FormulaC16H20N4O3S
CAS number
1654725-02-6
Molecular weight
348.42
Formula
C16H20N4O3S
Solubility
DMSO ： ≥ 250 mg/mL (717·52 mM)
InChIKey
GHTGYZMBQPXTCQ-UHFFFAOYSA-N
Catalogue number
GC19169
Brand
GLPBIO
Computed properties PubChem CID 117857370 · XLogP 1.8 · TPSA 138 Ų · H-bond donors 3
XLogP
1.8
TPSA
138 Ų
H-bond donors
3
H-bond acceptors
5
Rotatable bonds
3
Heavy atoms
24

SMILES CC1(CC2=C(C(O1)(C)C)SC(=C2C(=O)N)NC(=O)C3=CC=NN3)C

Computed descriptors from PubChem (CID 117857370), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.