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Chemical structure of GLPG2534

GC71226

GLPG2534

Also known as 6-[6-[2-(2-hydroxyethoxy)ethoxy]-5-(oxan-4-ylamino)imidazo[4,5-b]pyridin-3-yl]pyridine-3-carbonitrile

GLPG2534 is an orally active and selective IRAK4 inhibitor, with IC50 values of 6·4 nM and 3·5 nM for human and mouse IRAK4

ChemicalCAS2095615-97-5MW424.45FormulaC21H24N6O4
CAS number
2095615-97-5
Molecular weight
424.45
Formula
C21H24N6O4
Solubility
DMSO ： 100 mg/mL (235·60 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
InChIKey
VNAPWQDUDZCVCA-UHFFFAOYSA-N
Catalogue number
GC71226
Brand
GLPBIO
Computed properties PubChem CID 129053583 · XLogP 1.2 · TPSA 127 Ų · H-bond donors 2
XLogP
1.2
TPSA
127 Ų
H-bond donors
2
H-bond acceptors
9
Rotatable bonds
9
Heavy atoms
31

SMILES C1COCCC1NC2=C(C=C3C(=N2)N(C=N3)C4=NC=C(C=C4)C#N)OCCOCCO

Computed descriptors from PubChem (CID 129053583), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.