Loading...
Chemical structure of GLPG1690

GC19168

GLPG1690

Also known as 2-[[2-ethyl-6-[4-[2-(3-hydroxyazetidin-1-yl)-2-oxoethyl]piperazin-1-yl]-8-methylimidazo[1,2-a]pyridin-3-yl]-methylamino]-4-(4-fluorophenyl)-1,3-thiazole-5-carbonitrile

GLPG1690(Ziritaxestat) is a novel autotaxin (ATX) inhibitor with an IC50 of 131 nM and a Ki of 15 nM· It effectively halts the progression of idiopathic pulmonary fibrosis

ChemicalCAS1628260-79-6MW588.7FormulaC30H33FN8O2S
CAS number
1628260-79-6
Molecular weight
588.7
Formula
C30H33FN8O2S
Solubility
DMSO ： 41·67 mg/mL (70·78 mM);Water ： ＜ 0·1 mg/mL (insoluble)
InChIKey
REQQVBGILUTQNN-UHFFFAOYSA-N
Catalogue number
GC19168
Brand
GLPBIO
Computed properties PubChem CID 90420193 · XLogP 4.8 · TPSA 132 Ų · H-bond donors 1
XLogP
4.8
TPSA
132 Ų
H-bond donors
1
H-bond acceptors
10
Rotatable bonds
7
Heavy atoms
42

SMILES CCC1=C(N2C=C(C=C(C2=N1)C)N3CCN(CC3)CC(=O)N4CC(C4)O)N(C)C5=NC(=C(S5)C#N)C6=CC=C(C=C6)F

Computed descriptors from PubChem (CID 90420193), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.