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Chemical structure of MI-503

GC19247

MI-503

Also known as 4-methyl-1-(1H-pyrazol-4-ylmethyl)-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile

MI-503 is a highly potent and orally bioavailable small molecule inhibitor of the menin-mLL interaction

ChemicalCAS1857417-13-0MW564.63FormulaC28H27F3N8S
CAS number
1857417-13-0
Molecular weight
564.63
Formula
C28H27F3N8S
Solubility
DMSO ： 50 mg/mL (88·55 mM);Water ： ＜ 0·1 mg/mL (insoluble)
InChIKey
DETOMBLLEOZTMZ-UHFFFAOYSA-N
Catalogue number
GC19247
Brand
GLPBIO
Computed properties PubChem CID 91667931 · XLogP 5.8 · TPSA 127 Ų · H-bond donors 2
XLogP
5.8
TPSA
127 Ų
H-bond donors
2
H-bond acceptors
10
Rotatable bonds
7
Heavy atoms
40

SMILES CC1=C(C=CC2=C1C=C(N2CC3=CNN=C3)C#N)CN4CCC(CC4)NC5=C6C=C(SC6=NC=N5)CC(F)(F)F

Computed descriptors from PubChem (CID 91667931), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.