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Chemical structure of MI-463

GC19246

MI-463

Also known as 4-methyl-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-1H-indole-2-carbonitrile

MI-463 is a highly potent and orally bioavailable small molecule inhibitor of the menin-mLL interaction

ChemicalCAS1628317-18-9MW484.54FormulaC24H23F3N6S
CAS number
1628317-18-9
Molecular weight
484.54
Formula
C24H23F3N6S
Solubility
DMSO ： 125 mg/mL (257·98 mM);Water ： ＜ 0·1 mg/mL (insoluble)
InChIKey
DZACSLYTXLZAAF-UHFFFAOYSA-N
Catalogue number
GC19246
Brand
GLPBIO
Computed properties PubChem CID 90455046 · XLogP 5.9 · TPSA 109 Ų · H-bond donors 2
XLogP
5.9
TPSA
109 Ų
H-bond donors
2
H-bond acceptors
9
Rotatable bonds
5
Heavy atoms
34

SMILES CC1=C(C=CC2=C1C=C(N2)C#N)CN3CCC(CC3)NC4=C5C=C(SC5=NC=N4)CC(F)(F)F

Computed descriptors from PubChem (CID 90455046), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.