Loading...
Chemical structure of MI-538

GC32798

MI-538

Also known as 6-hydroxy-1-(1H-pyrazol-4-ylmethyl)-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile

MI-538 is an inhibitor of the interaction between menin and MLL fusion proteins with an IC50 of 21 nM

ChemicalCAS1857417-10-7MW566.6FormulaC27H25F3N8OS
CAS number
1857417-10-7
Molecular weight
566.6
Formula
C27H25F3N8OS
Solubility
DMSO ： 100 mg/mL (176·49 mM);Water ： ＜ 0·1 mg/mL (insoluble)
InChIKey
QXLJOBRSTCFLMC-UHFFFAOYSA-N
Catalogue number
GC32798
Brand
GLPBIO
Computed properties PubChem CID 117636625 · XLogP 5 · TPSA 147 Ų · H-bond donors 3
XLogP
5
TPSA
147 Ų
H-bond donors
3
H-bond acceptors
11
Rotatable bonds
7
Heavy atoms
40

SMILES C1CN(CCC1NC2=C3C=C(SC3=NC=N2)CC(F)(F)F)CC4=C(C=C5C(=C4)C=C(N5CC6=CNN=C6)C#N)O

Computed descriptors from PubChem (CID 117636625), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.