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Chemical structure of EGFR/ErbB2 Inhibitor

GC14856

EGFR/ErbB2 Inhibitor

Also known as 6,7-dimethoxy-N-(4-phenylmethoxyphenyl)quinazolin-4-amine

EGFR/ErbB2 Inhibitor (Compound 5) is a EGFR and ErbB inhibitor with IC50s of 0·017 μM, 0·08 μM, 1·91 μM

ChemicalCAS179248-61-4MW387.4FormulaC23H21N3O3
CAS number
179248-61-4
Molecular weight
387.4
Formula
C23H21N3O3
Solubility
≤1mg/ml in DMSO;10mg/ml in dimethyl formamide
InChIKey
DNOKYISWMVFYFA-UHFFFAOYSA-N
Catalogue number
GC14856
Brand
GLPBIO
Computed properties PubChem CID 9843206 · XLogP 4.8 · TPSA 65.5 Ų · H-bond donors 1
XLogP
4.8
TPSA
65.5 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
7
Heavy atoms
29

SMILES COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)OCC4=CC=CC=C4)OC

Computed descriptors from PubChem (CID 9843206), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.