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Chemical structure of RMC-6236

GC92066

RMC-6236

Also known as trans-(1S,2S)-N-[(7S,13S)-21-ethyl-20-[2-[(1S)-1-methoxyethyl]-5-(4-methylpiperazin-1-yl)-3-pyridinyl]-17,17-dimethyl-8,14-dioxo-15-oxa-4-thia-9,21,27,28-tetrazapentacyclo[17.5.2.12,5.19,13.022,26]octacosa-1(25),2,5(28),19,22(26),23-hexaen-7-yl]-2-methylcyclopropane-1-carboxamide

RMC-6236 is a non-covalent inhibitor of GTP-bound RAS

ChemicalCAS2765081-21-6MW811.1FormulaC44H58N8O5S
CAS number
2765081-21-6
Molecular weight
811.1
Formula
C44H58N8O5S
Solubility
DMSO： Sparingly soluble： 1–10 mg/ml,Ethanol： Sparingly soluble： 1–10 mg/ml
InChIKey
FVICRBSEYSHKFY-JYQNNKODSA-N
Catalogue number
GC92066
Brand
GLPBIO
Computed properties PubChem CID 164726578 · XLogP 5.1 · TPSA 162 Ų · H-bond donors 2
XLogP
5.1
TPSA
162 Ų
H-bond donors
2
H-bond acceptors
11
Rotatable bonds
7
Heavy atoms
58

SMILES CCN1C2=C3C=C(C=C2)C4=CSC(=N4)C[C@@H](C(=O)N5CCC[C@H](N5)C(=O)OCC(CC3=C1C6=C(N=CC(=C6)N7CCN(CC7)C)[C@H](C)OC)(C)C)NC(=O)[C@H]8C[C@@H]8C

Computed descriptors from PubChem (CID 164726578), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.