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Chemical structure of RMC-113

GC75747

RMC-113

Also known as 6-(3,4-dimethoxyphenyl)-3-(2-pyridin-3-ylethynyl)-[1,2]thiazolo[4,3-b]pyridine

RMC-113 is a PIP4K2C and PIKfyve inhibitor with the Ki vaules of 46 nM and 370 nM

ChemicalCAS2258606-34-5MW373.43FormulaC21H15N3O2S
CAS number
2258606-34-5
Molecular weight
373.43
Formula
C21H15N3O2S
Solubility
DMSO: 50 mg/mL (133·89 mM; ultrasonic and warming and heat to 60°C)
InChIKey
XMKRMXXCWCKTSQ-UHFFFAOYSA-N
Catalogue number
GC75747
Brand
GLPBIO
Computed properties PubChem CID 155542991 · XLogP 3.9 · TPSA 85.4 Ų · H-bond donors 0
XLogP
3.9
TPSA
85.4 Ų
H-bond donors
0
H-bond acceptors
6
Rotatable bonds
5
Heavy atoms
27

SMILES COC1=C(C=C(C=C1)C2=CC3=NSC(=C3N=C2)C#CC4=CN=CC=C4)OC

Computed descriptors from PubChem (CID 155542991), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Documents
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