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Chemical structure of EGFR T790M/L858R-IN-8

GC75812

EGFR T790M/L858R-IN-8

Also known as N-(3-bromophenyl)-4-hydroxy-2-oxo-1H-quinoline-3-carboxamide

EGFR T790M/L858R-IN-8 (compound 9) is a potent inhibitor of EGFR, targeting mutant EGFRT790M/L858R with IC50 of 56·8 μM

ChemicalCAS333419-97-9MW359.17FormulaC16H11BrN2O3
CAS number
333419-97-9
Molecular weight
359.17
Formula
C16H11BrN2O3
Solubility
DMSO： 2 mg/mL (5·57 mM; ultrasonic and warming and heat to 60°C)
InChIKey
UCCUKBQMSKZUOG-UHFFFAOYSA-N
Catalogue number
GC75812
Brand
GLPBIO
Computed properties PubChem CID 54678831 · XLogP 3 · TPSA 78.4 Ų · H-bond donors 3
XLogP
3
TPSA
78.4 Ų
H-bond donors
3
H-bond acceptors
3
Rotatable bonds
2
Heavy atoms
22

SMILES C1=CC=C2C(=C1)C(=C(C(=O)N2)C(=O)NC3=CC(=CC=C3)Br)O

Computed descriptors from PubChem (CID 54678831), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.