Loading...
Chemical structure of RMC-9805

GC73709

RMC-9805

Also known as (2S)-2-cyclopentyl-2-[(5S)-2-[(2R,3R)-3-cyclopropyl-1-methylaziridine-2-carbonyl]-2,7-diazaspiro[4.4]nonan-7-yl]-N-[(6S,8S,14S)-21-[5-(4-cyclopropylpiperazin-1-yl)-2-[(1S)-1-methoxyethyl]-3-pyridinyl]-18,18-dimethyl-9,15-dioxo-22-(2,2,2-trifluoroethyl)-5,16-dioxa-2,10,22,28-tetrazapentacyclo[18.5.2.12,6.110,14.023,27]nonacosa-1(26),20,23(27),24-tetraen-8-yl]acetamide

RMC-9805 (KRAS G12D inhibitor 18) is a KRAS G12D inhibitor

ChemicalCAS2922732-54-3MW1168.44FormulaC63H88F3N11O7
CAS number
2922732-54-3
Molecular weight
1168.44
Formula
C63H88F3N11O7
Solubility
DMSO ： 125 mg/mL (106·98 mM; Need ultrasonic)
InChIKey
VKNNQJWNUPSOEK-VCAAAJMFSA-N
Catalogue number
GC73709
Brand
GLPBIO
Computed properties PubChem CID 168201327 · XLogP 7.2 · TPSA 160 Ų · H-bond donors 2
XLogP
7.2
TPSA
160 Ų
H-bond donors
2
H-bond acceptors
17
Rotatable bonds
12
Heavy atoms
84

SMILES C[C@@H](C1=C(C=C(C=N1)N2CCN(CC2)C3CC3)C4=C5CC(COC(=O)[C@@H]6CCCN(N6)C(=O)[C@H](C[C@H]7CN(CCO7)C8=CC5=C(N4CC(F)(F)F)C=C8)NC(=O)[C@H](C9CCCC9)N1CC[C@@]2(C1)CCN(C2)C(=O)[C@H]1[C@H](N1C)C1CC1)(C)C)OC

Computed descriptors from PubChem (CID 168201327), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.