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Chemical structure of MS934

GC73498

MS934

Also known as (2S,4R)-1-[(2S)-2-[12-[4-[[3,4-difluoro-2-(2-fluoro-4-iodoanilino)benzoyl]amino]oxybutylamino]dodecanoylamino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]pyrrolidine-2-carboxamide

MS934 is a novel improved VHL-recruiting MEK 1/2 degrader

ChemicalCAS2756323-15-4MW1104.11FormulaC52H69F3IN7O6S
CAS number
2756323-15-4
Molecular weight
1104.11
Formula
C52H69F3IN7O6S
Solubility
DMSO ： ≥ 50 mg/mL (45·29 mM)
InChIKey
DYLGPTDXXUWFMK-ARFQKLFXSA-N
Catalogue number
GC73498
Brand
GLPBIO
Computed properties PubChem CID 162504450 · XLogP 11.3 · TPSA 202 Ų · H-bond donors 6
XLogP
11.3
TPSA
202 Ų
H-bond donors
6
H-bond acceptors
13
Rotatable bonds
28
Heavy atoms
70

SMILES CC1=C(SC=N1)C2=CC=C(C=C2)[C@H](C)NC(=O)[C@@H]3C[C@H](CN3C(=O)[C@H](C(C)(C)C)NC(=O)CCCCCCCCCCCNCCCCONC(=O)C4=C(C(=C(C=C4)F)F)NC5=C(C=C(C=C5)I)F)O

Computed descriptors from PubChem (CID 162504450), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.