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Chemical structure of GNE-7883

GC73127

GNE-7883

Also known as 5-(4-cyclohexylphenyl)-3-[3-(fluoromethyl)azetidine-1-carbonyl]-2-(3-methylpyrazin-2-yl)-1H-pyrazolo[1,5-a]pyrimidin-7-one

GNE-7883 is a pan-TEAD inhibitor that blocks the association of YAP/TAZ with TEAD

ChemicalCAS2648450-42-2MW500.57FormulaC28H29FN6O2
CAS number
2648450-42-2
Molecular weight
500.57
Formula
C28H29FN6O2
Solubility
DMSO ： 50 mg/mL (99·89 mM; Need ultrasonic)
InChIKey
OMGKSFJZXSXHCA-UHFFFAOYSA-N
Catalogue number
GC73127
Brand
GLPBIO
Computed properties PubChem CID 164852436 · XLogP 3.8 · TPSA 90.8 Ų · H-bond donors 1
XLogP
3.8
TPSA
90.8 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
5
Heavy atoms
37

SMILES CC1=NC=CN=C1C2=C(C3=NC(=CC(=O)N3N2)C4=CC=C(C=C4)C5CCCCC5)C(=O)N6CC(C6)CF

Computed descriptors from PubChem (CID 164852436), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.