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Chemical structure of PF-06445974

GC69692

PF-06445974

Also known as 4-(11-cyclopropyl-10-oxo-1,6,11-triazatricyclo[7.4.0.02,7]trideca-2(7),3,5,8-tetraen-8-yl)-2-fluorobenzonitrile

PF-06445974 is a positron emission tomography (PET) compound that effectively targets PDE4B with an IC50 of

ChemicalCAS2055776-17-3MW346.36FormulaC20H15FN4O
CAS number
2055776-17-3
Molecular weight
346.36
Formula
C20H15FN4O
Solubility
DMSO : 33·33 mg/mL (96·23 mM; ultrasonic and warming and heat to 60°C)
InChIKey
YWTCDMZVTLNYLN-UHFFFAOYSA-N
Catalogue number
GC69692
Brand
GLPBIO
Computed properties PubChem CID 124141261 · XLogP 2.5 · TPSA 61.9 Ų · H-bond donors 0
XLogP
2.5
TPSA
61.9 Ų
H-bond donors
0
H-bond acceptors
4
Rotatable bonds
2
Heavy atoms
26

SMILES C1CC1N2CCN3C4=C(C(=C3C2=O)C5=CC(=C(C=C5)C#N)F)N=CC=C4

Computed descriptors from PubChem (CID 124141261), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.