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Chemical structure of PF-06409577

GC19286

PF-06409577

Also known as 6-chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic acid

PF-06409577 is a potent and selective allosteric activator of AMPK α1β1γ1 isoform with an EC50 of 7 nM

ChemicalCAS1467057-23-3MW341.79FormulaC19H16ClNO3
CAS number
1467057-23-3
Molecular weight
341.79
Formula
C19H16ClNO3
Solubility
DMSO : ≥ 100 mg/mL (292·58 mM)
InChIKey
FHQXLWCFSUSXBF-UHFFFAOYSA-N
Catalogue number
GC19286
Brand
GLPBIO
Computed properties PubChem CID 71748255 · XLogP 3.6 · TPSA 73.3 Ų · H-bond donors 3
XLogP
3.6
TPSA
73.3 Ų
H-bond donors
3
H-bond acceptors
3
Rotatable bonds
3
Heavy atoms
24

SMILES C1CC(C1)(C2=CC=C(C=C2)C3=C(C=C4C(=C3)C(=CN4)C(=O)O)Cl)O

Computed descriptors from PubChem (CID 71748255), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.