
GC19286
PF-06409577
Also known as 6-chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic acid
PF-06409577 is a potent and selective allosteric activator of AMPK α1β1γ1 isoform with an EC50 of 7 nM
ChemicalCAS1467057-23-3MW341.79FormulaC19H16ClNO3
- CAS number
- 1467057-23-3
- Molecular weight
- 341.79
- Formula
- C19H16ClNO3
- Solubility
- DMSO : ≥ 100 mg/mL (292·58 mM)
- InChIKey
- FHQXLWCFSUSXBF-UHFFFAOYSA-N
- Catalogue number
- GC19286
- Brand
- GLPBIO
Computed properties PubChem CID 71748255 · XLogP 3.6 · TPSA 73.3 Ų · H-bond donors 3
- XLogP
- 3.6
- TPSA
- 73.3 Ų
- H-bond donors
- 3
- H-bond acceptors
- 3
- Rotatable bonds
- 3
- Heavy atoms
- 24
SMILES C1CC(C1)(C2=CC=C(C=C2)C3=C(C=C4C(=C3)C(=CN4)C(=O)O)Cl)O
Computed descriptors from PubChem (CID 71748255), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il