GC18959
PF-06424439
Also known as [(3R)-1-[2-[1-(4-chloropyrazol-1-yl)cyclopropyl]-1H-imidazo[4,5-b]pyridin-5-yl]piperidin-3-yl]-pyrrolidin-1-ylmethanone;methanesulfonic acid
PF-06424439 is a highly efficient and orally bioavailable selective diacylglycerol acyltransferase 2 (DGAT2) small molecule inhibitor with an IC50 value of 14nM
ChemicalCAS1469284-79-4MW536FormulaC22H26ClN7O·CH3SO3H
- CAS number
- 1469284-79-4
- Molecular weight
- 536
- Formula
- C22H26ClN7O·CH3SO3H
- Solubility
- DMSO ： 250 mg/mL (466·37 mM; Need ultrasonic); H2O ： 50 mg/mL (93·27 mM; Need ultrasonic)
- InChIKey
- ZSTFDNQQOJUJFL-XFULWGLBSA-N
- Catalogue number
- GC18959
- Brand
- GLPBIO
Computed properties PubChem CID 89854212 · TPSA 146 Ų · H-bond donors 2 · H-bond acceptors 8
- TPSA
- 146 Ų
- H-bond donors
- 2
- H-bond acceptors
- 8
- Rotatable bonds
- 4
- Heavy atoms
- 36
SMILES CS(=O)(=O)O.C1CCN(C1)C(=O)[C@@H]2CCCN(C2)C3=NC4=C(C=C3)NC(=N4)C5(CC5)N6C=C(C=N6)Cl
Computed descriptors from PubChem (CID 89854212), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il