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Chemical structure of ARV-766

GC68696

ARV-766

Also known as 4-[4-[[1-[4-[[3-(4-cyano-3-methoxyphenoxy)-2,2,4,4-tetramethylcyclobutyl]carbamoyl]phenyl]piperidin-4-yl]methyl]piperazin-1-yl]-N-[(3S)-2,6-dioxopiperidin-3-yl]-2-fluorobenzamide

ARV-766 is an orally effective protein degradation agent of protein hydrolysis targeted chimeras (PROTACs)· ARV-766 degrades wild-type androgen receptor AR, as well as related AR LBD mutants, including the most common pathogenic AR L702H, H875Y and T878A mutations

ChemicalCAS2750830-09-0MW807.95FormulaC45H54FN7O6
CAS number
2750830-09-0
Molecular weight
807.95
Formula
C45H54FN7O6
Solubility
DMSO ： 100 mg/mL (123·77 mM; Need ultrasonic)
InChIKey
RDPPBRKNBBXPNZ-PJXMSJPKSA-N
Catalogue number
GC68696
Brand
GLPBIO
Computed properties PubChem CID 156504141 · XLogP 5.9 · TPSA 156 Ų · H-bond donors 3
XLogP
5.9
TPSA
156 Ų
H-bond donors
3
H-bond acceptors
11
Rotatable bonds
11
Heavy atoms
59

SMILES CC1(C(C(C1OC2=CC(=C(C=C2)C#N)OC)(C)C)NC(=O)C3=CC=C(C=C3)N4CCC(CC4)CN5CCN(CC5)C6=CC(=C(C=C6)C(=O)N[C@H]7CCC(=O)NC7=O)F)C

Computed descriptors from PubChem (CID 156504141), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.