GC66002
PF-06685249
Also known as 6-chloro-5-[6-(dimethylamino)-2-methoxy-3-pyridinyl]-1H-indole-3-carboxylic acid
PF-06685249 (PF-249) is a potent and orally active allosteric AMPK activator with an EC50 of 12 nM for recombinant AMPK α1β1γ1· PF-06685249 can be used for diabetic nephropathy research
ChemicalCAS1467059-70-6MW345.78FormulaC17H16ClN3O3
- CAS number
- 1467059-70-6
- Molecular weight
- 345.78
- Formula
- C17H16ClN3O3
- Solubility
- DMSO ： 100 mg/mL (289·20 mM; Need ultrasonic)
- InChIKey
- MJHBRTGGZYSCHJ-UHFFFAOYSA-N
- Catalogue number
- GC66002
- Brand
- GLPBIO
Computed properties PubChem CID 71767991 · XLogP 3.5 · TPSA 78.5 Ų · H-bond donors 2
- XLogP
- 3.5
- TPSA
- 78.5 Ų
- H-bond donors
- 2
- H-bond acceptors
- 5
- Rotatable bonds
- 4
- Heavy atoms
- 24
SMILES CN(C)C1=NC(=C(C=C1)C2=C(C=C3C(=C2)C(=CN3)C(=O)O)Cl)OC
Computed descriptors from PubChem (CID 71767991), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il