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Chemical structure of PF-06651600

GC19288

PF-06651600

Also known as 1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)piperidin-1-yl]prop-2-en-1-one

PF-06651600 (PF-06651600) is an orally active and selective JAK3 inhibitor with an IC50 of 33·1 nM

ChemicalCAS1792180-81-4MW285.34FormulaC15H19N5O
CAS number
1792180-81-4
Molecular weight
285.34
Formula
C15H19N5O
Solubility
DMSO : 150 mg/mL (525·69 mM)
InChIKey
CBRJPFGIXUFMTM-WDEREUQCSA-N
Catalogue number
GC19288
Brand
GLPBIO
Computed properties PubChem CID 118115473 · XLogP 2.1 · TPSA 73.9 Ų · H-bond donors 2
XLogP
2.1
TPSA
73.9 Ų
H-bond donors
2
H-bond acceptors
4
Rotatable bonds
3
Heavy atoms
21

SMILES C[C@H]1CC[C@H](CN1C(=O)C=C)NC2=NC=NC3=C2C=CN3

Computed descriptors from PubChem (CID 118115473), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.