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Chemical structure of Brepocitinib Tosylate

GC19405

Brepocitinib Tosylate

Also listed as PF-06700841 P-Tosylate

Brepocitinib (PF-06700841) P-Tosylate is a potent dual Janus kinase 1 (JAK1) and TYK2 inhibitor with IC50s of 17 nM and 23 nM, respectively

ChemicalCAS2140301-96-6MW561.61FormulaC25H29F2N7O4S
CAS number
2140301-96-6
Molecular weight
561.61
Formula
C25H29F2N7O4S
Solubility
DMSO : 62·5 mg/mL (111·29 mM)
InChIKey
FAKGOYNHHHOTEN-VDTKTRGNSA-N
Catalogue number
GC19405
Brand
GLPBIO
Computed properties PubChem CID 124203834 · TPSA 142 Ų · H-bond donors 2 · H-bond acceptors 11
TPSA
142 Ų
H-bond donors
2
H-bond acceptors
11
Rotatable bonds
5
Heavy atoms
39

SMILES CC1=CC=C(C=C1)S(=O)(=O)O.CN1C=C(C=N1)NC2=NC=CC(=N2)N3C[C@H]4CC[C@@H](C3)N4C(=O)[C@@H]5CC5(F)F

Computed descriptors from PubChem (CID 124203834), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.