GC65904
KRAS G12C inhibitor 28
Also known as 1-(4-dimethylphosphoryl-2-methyl-6-propan-2-ylphenyl)-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-[(2S)-2-methyl-4-prop-2-enoylpiperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
KRAS G12C inhibitor 28 is a KRAS G12C inhibitor with an IC50 of 57 nM· KRAS G12C inhibitor 28 has antitumor effects (WO2021113595A1; Example 1)
ChemicalCAS2649004-88-4MW635.64FormulaC33H36F2N5O4P
- CAS number
- 2649004-88-4
- Molecular weight
- 635.64
- Formula
- C33H36F2N5O4P
- InChIKey
- AULVAQHFJPQQED-FQEVSTJZSA-N
- Catalogue number
- GC65904
- Brand
- GLPBIO
Computed properties PubChem CID 156443495 · XLogP 4 · TPSA 106 Ų · H-bond donors 1
- XLogP
- 4
- TPSA
- 106 Ų
- H-bond donors
- 1
- H-bond acceptors
- 7
- Rotatable bonds
- 6
- Heavy atoms
- 45
SMILES C[C@H]1CN(CCN1C2=NC(=O)N(C3=NC(=C(C=C32)F)C4=C(C=CC=C4F)O)C5=C(C=C(C=C5C)P(=O)(C)C)C(C)C)C(=O)C=C
Computed descriptors from PubChem (CID 156443495), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il