GC64442
KRAS G12C inhibitor 14
Also known as (7R)-16-chloro-14-fluoro-15-(2-fluoro-6-hydroxyphenyl)-9-methyl-5-prop-2-enoyl-2,5,9,12-tetrazatetracyclo[8.8.0.02,7.013,18]octadeca-1(10),11,13,15,17-pentaen-8-one
KRAS G12C inhibitor 14 is a potent KRAS G12C inhibitor extracted from patent WO2019110751A1, compound 17, has an IC50 of 18 nM
ChemicalCAS2349393-95-7MW484.88FormulaC24H19ClF2N4O3
- CAS number
- 2349393-95-7
- Molecular weight
- 484.88
- Formula
- C24H19ClF2N4O3
- Solubility
- DMSO ： 100 mg/mL (206·24 mM; Need ultrasonic)
- InChIKey
- NZIBTXKFKUORFB-MRXNPFEDSA-N
- Catalogue number
- GC64442
- Brand
- GLPBIO
Computed properties PubChem CID 138678756 · XLogP 3.5 · TPSA 77 Ų · H-bond donors 1
- XLogP
- 3.5
- TPSA
- 77 Ų
- H-bond donors
- 1
- H-bond acceptors
- 7
- Rotatable bonds
- 2
- Heavy atoms
- 34
SMILES CN1C2=C(C3=CC(=C(C(=C3N=C2)F)C4=C(C=CC=C4F)O)Cl)N5CCN(C[C@@H]5C1=O)C(=O)C=C
Computed descriptors from PubChem (CID 138678756), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il