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Chemical structure of KRAS inhibitor-10

GC62486

KRAS inhibitor-10

Also known as 7-[2-(3-amino-4-methoxyphenyl)ethoxy]-N-ethyl-6-methoxy-1-(4-methoxy-2-methylphenyl)-3,4-dihydro-1H-isoquinoline-2-carboxamide

KRAS inhibitor-10 selectively and effectively inhibit RAS proteins, and particularly KRAS proteins· KRAS inhibitor-10 is an orally active anti-cancer agent and can be used for cancer research, such as pancreatic cancer, breast cancer, multiple myeloma, leukemia and lung cancer· KRAS inhibitor-10 is a?tetrahydroisoquinoline compound (compound 11) extracted from patent WO2021005165 A1

ChemicalCAS2578876-75-0MW519.63FormulaC30H37N3O5
CAS number
2578876-75-0
Molecular weight
519.63
Formula
C30H37N3O5
Solubility
DMSO ： 100 mg/mL (192·44 mM; Need ultrasonic)
InChIKey
WKOOIGPIJNQBPY-UHFFFAOYSA-N
Catalogue number
GC62486
Brand
GLPBIO
Computed properties PubChem CID 155471755 · XLogP 4.7 · TPSA 95.3 Ų · H-bond donors 2
XLogP
4.7
TPSA
95.3 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
9
Heavy atoms
38

SMILES CCNC(=O)N1CCC2=CC(=C(C=C2C1C3=C(C=C(C=C3)OC)C)OCCC4=CC(=C(C=C4)OC)N)OC

Computed descriptors from PubChem (CID 155471755), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.