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Chemical structure of GNE-502

GC65590

GNE-502

Also known as (1R,3R)-1-[4-[2-[3-(fluoromethyl)azetidin-1-yl]ethoxy]phenyl]-3-methyl-2-methylsulfonyl-1,3,4,9-tetrahydropyrido[3,4-b]indole

GNE-502 is an orally active and potent degrader for estrogen receptor (ER)· GNE-502 can be used for the research of breast cancer

ChemicalCAS1953134-16-1MW471.59FormulaC25H30FN3O3S
CAS number
1953134-16-1
Molecular weight
471.59
Formula
C25H30FN3O3S
Solubility
DMSO ： 100 mg/mL (212·05 mM; Need ultrasonic)
InChIKey
ALLRPIPLWLLBGX-CRICUBBOSA-N
Catalogue number
GC65590
Brand
GLPBIO
Computed properties PubChem CID 121410723 · XLogP 3.7 · TPSA 74 Ų · H-bond donors 1
XLogP
3.7
TPSA
74 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
7
Heavy atoms
33

SMILES C[C@@H]1CC2=C([C@H](N1S(=O)(=O)C)C3=CC=C(C=C3)OCCN4CC(C4)CF)NC5=CC=CC=C25

Computed descriptors from PubChem (CID 121410723), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.