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Chemical structure of (S,R,S)-AHPC-Me dihydrochloride

GC60426

(S,R,S)-AHPC-Me dihydrochloride

(S,R,S)-AHPC-Me dihydrochloride (VHL ligand 2 dihydrochloride) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein· (S,R,S)-AHPC-Me dihydrochloride can be used to synthesize ARV-771, a von Hippel-Landau (VHL) E3 ligase-based BET PROTAC degrader· ARV-771 potently degrades BET protein in castration-resistant prostate cancer (CRPC) cells with a DC50 ＜1 nM

ChemicalMW517.51FormulaC23H34Cl2N4O3S
CAS number
—
Molecular weight
517.51
Formula
C23H34Cl2N4O3S
Solubility
DMSO： 100 mg/mL (193·23 mM)
Catalogue number
GC60426
Brand
GLPBIO

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.