Loading...
Chemical structure of (S,R,S)-AHPC-C5-COOH

GC65133

(S,R,S)-AHPC-C5-COOH

Also known as 7-[[(2S)-1-[(2S,4R)-4-hydroxy-2-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methylcarbamoyl]pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]amino]heptanoic acid

(S,R,S)-AHPC-C5-COOH (VH032-C5-COOH) is a synthesized?E3 ligase ligand-linker conjugate, contains the VH032 VHL-based ligand and a linker to form PROTACs· VH-032 is a selective and potent inhibitor of VHL/HIF-1α interaction with a Kd of 185 nM, has the potential for the study of anemia and ischemic diseases

ChemicalCAS2267282-19-7MW558.73FormulaC29H42N4O5S
CAS number
2267282-19-7
Molecular weight
558.73
Formula
C29H42N4O5S
InChIKey
SCVBFBWIXTXYQE-MVERNJQCSA-N
Catalogue number
GC65133
Brand
GLPBIO
Computed properties PubChem CID 145709970 · XLogP 1.4 · TPSA 160 Ų · H-bond donors 4
XLogP
1.4
TPSA
160 Ų
H-bond donors
4
H-bond acceptors
8
Rotatable bonds
14
Heavy atoms
39

SMILES CC1=C(SC=N1)C2=CC=C(C=C2)CNC(=O)[C@@H]3C[C@H](CN3C(=O)[C@H](C(C)(C)C)NCCCCCCC(=O)O)O

Computed descriptors from PubChem (CID 145709970), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.