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Chemical structure of (S,R,S)-AHPC-C6-NH2

GC62007

(S,R,S)-AHPC-C6-NH2

Also known as (2S,4R)-1-[(2S)-2-(7-aminoheptanoylamino)-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide

(S,R,S)-AHPC-C6-NH2 (VH032-C6-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in?PROTAC?technology

ChemicalCAS2306389-03-5MW557.75FormulaC29H43N5O4S
CAS number
2306389-03-5
Molecular weight
557.75
Formula
C29H43N5O4S
InChIKey
MOCAYTDKEHDJAK-MVERNJQCSA-N
Catalogue number
GC62007
Brand
GLPBIO
Computed properties PubChem CID 138693510 · XLogP 2.9 · TPSA 166 Ų · H-bond donors 4
XLogP
2.9
TPSA
166 Ų
H-bond donors
4
H-bond acceptors
7
Rotatable bonds
13
Heavy atoms
39

SMILES CC1=C(SC=N1)C2=CC=C(C=C2)CNC(=O)[C@@H]3C[C@H](CN3C(=O)[C@H](C(C)(C)C)NC(=O)CCCCCCN)O

Computed descriptors from PubChem (CID 138693510), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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