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Chemical structure of AMG-Tie2-1

GC45809

AMG-Tie2-1

Also known as 4-methyl-3-[[3-[2-(methylamino)pyrimidin-4-yl]-2-pyridinyl]oxy]-N-[3-(trifluoromethyl)phenyl]benzamide

A Tie2 and VEGFR2 inhibitor

ChemicalCAS870223-96-4MW479.5FormulaC25H20F3N5O2
CAS number
870223-96-4
Molecular weight
479.5
Formula
C25H20F3N5O2
Solubility
DMF： 10mg/mL,DMSO： 10mg/mL,DMSO：PBS (pH 7·2) (1：2)： 0·3mg/mL
InChIKey
ZVIWALRWYYSHSU-UHFFFAOYSA-N
Catalogue number
GC45809
Brand
GLPBIO
Computed properties PubChem CID 16108977 · XLogP 5.1 · TPSA 89 Ų · H-bond donors 2
XLogP
5.1
TPSA
89 Ų
H-bond donors
2
H-bond acceptors
9
Rotatable bonds
6
Heavy atoms
35

SMILES CC1=C(C=C(C=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)OC3=C(C=CC=N3)C4=NC(=NC=C4)NC

Computed descriptors from PubChem (CID 16108977), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.