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Chemical structure of AMG 548

GC14899

AMG 548

Also known as 2-[[(2S)-2-amino-3-phenylpropyl]amino]-3-methyl-5-naphthalen-2-yl-6-pyridin-4-ylpyrimidin-4-one

P38α inhibitor,potent and selective

ChemicalCAS864249-60-5MW461.56FormulaC29H27N5O
CAS number
864249-60-5
Molecular weight
461.56
Formula
C29H27N5O
Solubility
＜49·8mg/ml in DMSO; ＜49·8mg/ml in ethanol
InChIKey
RQVKVJIRFKVPBF-VWLOTQADSA-N
Catalogue number
GC14899
Brand
GLPBIO
Computed properties PubChem CID 11167112 · XLogP 3.8 · TPSA 83.6 Ų · H-bond donors 2
XLogP
3.8
TPSA
83.6 Ų
H-bond donors
2
H-bond acceptors
4
Rotatable bonds
7
Heavy atoms
35

SMILES CN1C(=O)C(=C(N=C1NC[C@H](CC2=CC=CC=C2)N)C3=CC=NC=C3)C4=CC5=CC=CC=C5C=C4

Computed descriptors from PubChem (CID 11167112), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.