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Chemical structure of BI-2852

GC35513

BI-2852

Also known as (3S)-5-hydroxy-3-[2-[[[1-[(1-methylimidazol-4-yl)methyl]indol-6-yl]methylamino]methyl]-1H-indol-3-yl]-2,3-dihydroisoindol-1-one

BI-2852 is a KRAS inhibitor for the switch I/II pocket (SI/II-pocket) by structure-based drug design with nanomolar affinity

ChemicalCAS2375482-51-0MW516.59FormulaC31H28N6O2
CAS number
2375482-51-0
Molecular weight
516.59
Formula
C31H28N6O2
Solubility
DMSO： 55 mg/mL (106·47 mM)
InChIKey
JYEQLXOWWLNVDX-PMERELPUSA-N
Catalogue number
GC35513
Brand
GLPBIO
Computed properties PubChem CID 138756246 · XLogP 2.9 · TPSA 99.9 Ų · H-bond donors 4
XLogP
2.9
TPSA
99.9 Ų
H-bond donors
4
H-bond acceptors
4
Rotatable bonds
7
Heavy atoms
39

SMILES CN1C=C(N=C1)CN2C=CC3=C2C=C(C=C3)CNCC4=C(C5=CC=CC=C5N4)[C@@H]6C7=C(C=CC(=C7)O)C(=O)N6

Computed descriptors from PubChem (CID 138756246), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.