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Chemical structure of BI-2493

GC73477

BI-2493

Also known as (7S)-2'-amino-3-[2-[(2S)-2-methylpiperazin-1-yl]pyrimidin-4-yl]spiro[5,6-dihydro-4H-1,2-benzoxazole-7,4'-6,7-dihydro-5H-1-benzothiophene]-3'-carbonitrile

BI-2493 is a structural analogue of BI-2865 and a highly selective and orally active pan-KRAS inhibitor

ChemicalCAS2937344-16-4MW461.58FormulaC24H27N7OS
CAS number
2937344-16-4
Molecular weight
461.58
Formula
C24H27N7OS
Solubility
DMSO ： 50 mg/mL (108·32 mM; Need ultrasonic)
InChIKey
PVOYBVVIBNPTPJ-BSEYFRJRSA-N
Catalogue number
GC73477
Brand
GLPBIO
Computed properties PubChem CID 168268198 · XLogP 3.7 · TPSA 145 Ų · H-bond donors 2
XLogP
3.7
TPSA
145 Ų
H-bond donors
2
H-bond acceptors
9
Rotatable bonds
2
Heavy atoms
33

SMILES C[C@H]1CNCCN1C2=NC=CC(=N2)C3=NOC4=C3CCC[C@@]45CCCC6=C5C(=C(S6)N)C#N

Computed descriptors from PubChem (CID 168268198), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.