Loading...
Chemical structure of AMG 925 HCl

GC35315

AMG 925 HCl

Also known as 2-hydroxy-1-[2-[[8-(4-methylcyclohexyl)-4,6,8,11-tetrazatricyclo[7.4.0.02,7]trideca-1(9),2,4,6,10,12-hexaen-5-yl]amino]-7,8-dihydro-5H-1,6-naphthyridin-6-yl]ethanone;hydrochloride

AMG 925 HCl is a potent, selective, and orally available FLT3/CDK4 dual inhibitor with IC50s of 2±1 nM and 3±1 nM, respectively

ChemicalCAS1401034-19-2MW508.02FormulaC26H30ClN7O2
CAS number
1401034-19-2
Molecular weight
508.02
Formula
C26H30ClN7O2
Solubility
DMSO： 1 mg/mL (1·97 mM)
InChIKey
JJDSFFVYZSLRLY-UHFFFAOYSA-N
Catalogue number
GC35315
Brand
GLPBIO
Computed properties PubChem CID 121371122 · TPSA 109 Ų · H-bond donors 3 · H-bond acceptors 7
TPSA
109 Ų
H-bond donors
3
H-bond acceptors
7
Rotatable bonds
4
Heavy atoms
36

SMILES CC1CCC(CC1)N2C3=C(C=CN=C3)C4=CN=C(N=C42)NC5=NC6=C(CN(CC6)C(=O)CO)C=C5.Cl

Computed descriptors from PubChem (CID 121371122), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.