GC33325
VX-984 (M9831)
Also known as 8-[(2S)-1-[[6-(4,6-dideuterio-2-methylpyrimidin-5-yl)pyrimidin-4-yl]amino]propan-2-yl]-N-methylquinoline-4-carboxamide
VX-984 (M9831) (M9831) is an orally active, potent, selective and BBB-penetrated DNA-PK inhibitor· VX-984 (M9831) efficiently inhibits NHEJ (non-homologous end joining) and increases DSBs (DNA double-strand breaks)· VX-984 (M9831) can be used for glioblastomas (GBM) and non-small cell lung cancer (NSCLC) research
ChemicalCAS1476074-39-1MW415.49FormulaC23H21D2N7O
- CAS number
- 1476074-39-1
- Molecular weight
- 415.49
- Formula
- C23H21D2N7O
- Solubility
- DMSO ： 8·33 mg/mL (20·05 mM)
- InChIKey
- PEACIOGDEQRHFA-KIYKJNLWSA-N
- Catalogue number
- GC33325
- Brand
- GLPBIO
Computed properties PubChem CID 72188357 · XLogP 2.7 · TPSA 106 Ų · H-bond donors 2
- XLogP
- 2.7
- TPSA
- 106 Ų
- H-bond donors
- 2
- H-bond acceptors
- 7
- Rotatable bonds
- 6
- Heavy atoms
- 31
SMILES [2H]C1=C(C(=NC(=N1)C)[2H])C2=CC(=NC=N2)NC[C@@H](C)C3=CC=CC4=C(C=CN=C43)C(=O)NC
Computed descriptors from PubChem (CID 72188357), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il