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Chemical structure of VY-3-135

GC64681

VY-3-135

Also known as 3-ethyl-2-[hydroxy(diphenyl)methyl]-N-[(2R)-2-hydroxypropyl]benzimidazole-5-carboxamide

VY-3-135 is a potent and orally stable ACSS2 inhibitor with an IC50 value of 44±3·85nM and a water solubility of 21·7μM

ChemicalCAS1824637-41-3MW429.51FormulaC26H27N3O3
CAS number
1824637-41-3
Molecular weight
429.51
Formula
C26H27N3O3
Solubility
DMSO : 100 mg/mL (232·82 mM; Need ultrasonic)
InChIKey
KTPYOTKTDCLZHR-GOSISDBHSA-N
Catalogue number
GC64681
Brand
GLPBIO
Computed properties PubChem CID 92131155 · XLogP 3.1 · TPSA 87.4 Ų · H-bond donors 3
XLogP
3.1
TPSA
87.4 Ų
H-bond donors
3
H-bond acceptors
4
Rotatable bonds
7
Heavy atoms
32

SMILES CCN1C2=C(C=CC(=C2)C(=O)NC[C@@H](C)O)N=C1C(C3=CC=CC=C3)(C4=CC=CC=C4)O

Computed descriptors from PubChem (CID 92131155), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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