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Chemical structure of SEL120-34A

GC33137

SEL120-34A

Also known as 6,7-dibromo-5-methyl-2-piperazin-1-yl-1,3-diazatricyclo[6.3.1.04,12]dodeca-2,4,6,8(12)-tetraene

SEL120-34A is a potent, selective, orally available, ATP-competitive CDK8 inhibitor, with IC50s of 4·4 nM and 10·4 nM for CDK8/CycC and CDK19/CycC, respectively, with antitumor activity

ChemicalCAS1609522-33-9MW414.14FormulaC15H18Br2N4
CAS number
1609522-33-9
Molecular weight
414.14
Formula
C15H18Br2N4
Solubility
Soluble in DMSO
InChIKey
FSBMCTDYWXIBLM-UHFFFAOYSA-N
Catalogue number
GC33137
Brand
GLPBIO
Computed properties PubChem CID 73776233 · XLogP 3.3 · TPSA 33.1 Ų · H-bond donors 1
XLogP
3.3
TPSA
33.1 Ų
H-bond donors
1
H-bond acceptors
3
Rotatable bonds
1
Heavy atoms
21

SMILES CC1=C2C3=C(CCCN3C(=N2)N4CCNCC4)C(=C1Br)Br

Computed descriptors from PubChem (CID 73776233), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.