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Chemical structure of SEL24-B489

GC64774

SEL24-B489

Also known as 5,6-dibromo-4-nitro-2-piperidin-4-yl-1-propan-2-ylbenzimidazole

SEL24-B489 is a potent, type I, orally active, dual PIM and FLT3-ITD inhibitor, with Kd values of 2 nM for PIM1, 2 nM for PIM2 and 3 nM for PIM3, respectively

ChemicalCAS1616359-00-2MW446.14FormulaC15H18Br2N4O2
CAS number
1616359-00-2
Molecular weight
446.14
Formula
C15H18Br2N4O2
Solubility
DMSO ： 25 mg/mL (56·04 mM; ultrasonic and adjust pH to 2 with HCl)
InChIKey
UOUBCIJIWDLRGM-UHFFFAOYSA-N
Catalogue number
GC64774
Brand
GLPBIO
Computed properties PubChem CID 76286825 · XLogP 3.5 · TPSA 75.7 Ų · H-bond donors 1
XLogP
3.5
TPSA
75.7 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
2
Heavy atoms
23

SMILES CC(C)N1C2=CC(=C(C(=C2N=C1C3CCNCC3)[N+](=O)[O-])Br)Br

Computed descriptors from PubChem (CID 76286825), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.