GC18947
PF-05089771 (tosylate)
Also known as 4-[2-(5-amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-(1,3-thiazol-4-yl)benzenesulfonamide;4-methylbenzenesulfonic acid
PF-05089771 is a voltage-gated sodium channel 1·7 (Nav1·7) blocker (IC50s = 11, 16, 33, and 20 nM for 5N11S, 5A11L, 5A11S, and 5A11L Nav1·7 splice variants, respectively)
ChemicalCAS1430806-04-4MW672.6FormulaC18H12Cl2FN5O3S2·C7H8O3S
- CAS number
- 1430806-04-4
- Molecular weight
- 672.6
- Formula
- C18H12Cl2FN5O3S2·C7H8O3S
- Solubility
- DMSO ： ≥ 34 mg/mL (67·95 mM)
- InChIKey
- NVKBPDYKPNYMDR-UHFFFAOYSA-N
- Catalogue number
- GC18947
- Brand
- GLPBIO
Computed properties PubChem CID 71554187 · TPSA 222 Ų · H-bond donors 4 · H-bond acceptors 12
- TPSA
- 222 Ų
- H-bond donors
- 4
- H-bond acceptors
- 12
- Rotatable bonds
- 7
- Heavy atoms
- 42
SMILES CC1=CC=C(C=C1)S(=O)(=O)O.C1=CC(=C(C=C1Cl)C2=C(NN=C2)N)OC3=CC(=C(C=C3Cl)S(=O)(=O)NC4=CSC=N4)F
Computed descriptors from PubChem (CID 71554187), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il