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Chemical structure of PF-06649298

GC66038

PF-06649298

Also known as (2R)-2-[2-(4-tert-butylphenyl)ethyl]-2-hydroxybutanedioic acid

PF-06649298 is a sodium-coupled citrate transporter (NaCT or SLC13A5) inhibitor· PF-06649298 specifically interacts with NaCT with an IC50 value of 16·2 μM to inhibits the transport of citrate in human hepatocytes· PF-06649298 can be used for the research of regulating glucose metabolism and lipid metabolism

ChemicalCAS1854061-16-7MW294.34FormulaC16H22O5
CAS number
1854061-16-7
Molecular weight
294.34
Formula
C16H22O5
Solubility
DMSO ： 100 mg/mL (339·74 mM; Need ultrasonic)
InChIKey
QNFWRHKLBLSSPB-MRXNPFEDSA-N
Catalogue number
GC66038
Brand
GLPBIO
Computed properties PubChem CID 127029348 · XLogP 2.5 · TPSA 94.8 Ų · H-bond donors 3
XLogP
2.5
TPSA
94.8 Ų
H-bond donors
3
H-bond acceptors
5
Rotatable bonds
7
Heavy atoms
21

SMILES CC(C)(C)C1=CC=C(C=C1)CC[C@@](CC(=O)O)(C(=O)O)O

Computed descriptors from PubChem (CID 127029348), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.