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Chemical structure of AMG-3969

GC19029

AMG-3969

Also known as 2-[4-[(2S)-4-[(6-amino-3-pyridinyl)sulfonyl]-2-prop-1-ynylpiperazin-1-yl]phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol

AMG-3969 is a potent glucokinase-glucokinase regulatory protein interaction (GK-GKRP) disruptor with an IC50 of 4 nM

ChemicalCAS1361224-53-4MW522.46FormulaC21H20F6N4O3S
CAS number
1361224-53-4
Molecular weight
522.46
Formula
C21H20F6N4O3S
Solubility
DMSO ： ≥ 100 mg/mL (191·40 mM)
InChIKey
SIFKNECWLVONIH-INIZCTEOSA-N
Catalogue number
GC19029
Brand
GLPBIO
Computed properties PubChem CID 73053709 · XLogP 3.1 · TPSA 108 Ų · H-bond donors 2
XLogP
3.1
TPSA
108 Ų
H-bond donors
2
H-bond acceptors
13
Rotatable bonds
4
Heavy atoms
35

SMILES CC#C[C@H]1CN(CCN1C2=CC=C(C=C2)C(C(F)(F)F)(C(F)(F)F)O)S(=O)(=O)C3=CN=C(C=C3)N

Computed descriptors from PubChem (CID 73053709), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.