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Chemical structure of ORIC-944

GC73784

ORIC-944

Also known as 8-[4-[(dimethylamino)methyl]-2-methylphenyl]-5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]imidazo[1,2-c]pyrimidine-2-carbonitrile

ORIC-944 is a selective, orally active, allosteric inhibitor targeting the EED subunit of polycomb repressive complex 2 (PRC2)

ChemicalCAS2369769-29-7MW456.51FormulaC26H25FN6O
CAS number
2369769-29-7
Molecular weight
456.51
Formula
C26H25FN6O
Solubility
DMSO ： 100 mg/mL (219·05 mM; Need ultrasonic)
InChIKey
FLCIOLFIDGTRCI-UHFFFAOYSA-N
Catalogue number
GC73784
Brand
GLPBIO
Computed properties PubChem CID 155788096 · XLogP 4.9 · TPSA 78.5 Ų · H-bond donors 1
XLogP
4.9
TPSA
78.5 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
6
Heavy atoms
34

SMILES CC1=C(C=CC(=C1)CN(C)C)C2=CN=C(N3C2=NC(=C3)C#N)NCC4=C(C=CC5=C4CCO5)F

Computed descriptors from PubChem (CID 155788096), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.