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Chemical structure of ORM-15341

GC32402

ORM-15341

Also known as 3-acetyl-N-[(2S)-1-[3-(3-chloro-4-cyanophenyl)pyrazol-1-yl]propan-2-yl]-1H-pyrazole-5-carboxamide

ORM-15341 is a potent and full antagonist for human AR (hAR) with IC50 values of 38 nM as shown by transactivation assays in AR-HEK293 cells stably expressing full-length hAR and an androgen-responsive luciferase reporter gene construct

ChemicalCAS1297537-33-7MW396.83FormulaC19H17ClN6O2
CAS number
1297537-33-7
Molecular weight
396.83
Formula
C19H17ClN6O2
Solubility
DMSO ： ≥ 37 mg/mL (93·24 mM)
InChIKey
GMBPVBVTPBWIKC-NSHDSACASA-N
Catalogue number
GC32402
Brand
GLPBIO
Computed properties PubChem CID 52919826 · XLogP 2.2 · TPSA 116 Ų · H-bond donors 2
XLogP
2.2
TPSA
116 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
6
Heavy atoms
28

SMILES C[C@@H](CN1C=CC(=N1)C2=CC(=C(C=C2)C#N)Cl)NC(=O)C3=CC(=NN3)C(=O)C

Computed descriptors from PubChem (CID 52919826), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.